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rabbit polyclonal anti doublecortin primary antibody  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc rabbit polyclonal anti doublecortin primary antibody
    Neurogenesis is impaired with age in the Diversity Outbred mouse model and reduced relative to C57BL/6J inbred mice. A Representative confocal microscopy images of the dentate gyrus (DG) of adult (6 month) and aged (18 month) C57BL/6J mice stained for <t>Doublecortin</t> (DCX) (green). B Quantification of the numbers of the average DCX-positive cells in the DG of adult and aged C57BL/6J mice (Mann Whitney U test, * p = 0.0159, n = 5 adult mice, n = 4 aged mice). C Representative confocal microscopy images of the dentate gyrus of adult (6 month) and aged (18 month) Diversity Outbred mice stained for DCX (green). D Quantification of the average DCX-positive cells in the DG of adult and aged Diversity Outbred mice (Mann Whitney test, ** p = 0.0043, n = 5 adult mice, n = 5 aged mice). E Log2 fold change of the average DCX-positive cells between adult and aged C57BL/6J mice and adult and aged DO mice. F Average DCX-positive cells in the DG of adult C57BL/6J and DO mice (Mann Whitney test, * p = 0.0317, n = 5 adult C57BL/6J mice, n = 5 adult DO mice). G Average DCX-positive cells in the DG of aged C57BL/6J and DO mice (Mann Whitney test, p = 0.1143, n = 4 aged C57BL/6J mice, n = 6 aged DO mice)
    Rabbit Polyclonal Anti Doublecortin Primary Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 995 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+polyclonal+anti+doublecortin+primary+antibody/Doublecortin+Antibody/pmc12972464-36-25-31
    Average 96 stars, based on 995 article reviews
    rabbit polyclonal anti doublecortin primary antibody - by Bioz Stars, 2026-09
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    1) Product Images from "Characterization of adult hippocampal neurogenesis in adult and aged genetically diverse mice"

    Article Title: Characterization of adult hippocampal neurogenesis in adult and aged genetically diverse mice

    Journal: GeroScience

    doi: 10.1007/s11357-025-01749-9

    Neurogenesis is impaired with age in the Diversity Outbred mouse model and reduced relative to C57BL/6J inbred mice. A Representative confocal microscopy images of the dentate gyrus (DG) of adult (6 month) and aged (18 month) C57BL/6J mice stained for Doublecortin (DCX) (green). B Quantification of the numbers of the average DCX-positive cells in the DG of adult and aged C57BL/6J mice (Mann Whitney U test, * p = 0.0159, n = 5 adult mice, n = 4 aged mice). C Representative confocal microscopy images of the dentate gyrus of adult (6 month) and aged (18 month) Diversity Outbred mice stained for DCX (green). D Quantification of the average DCX-positive cells in the DG of adult and aged Diversity Outbred mice (Mann Whitney test, ** p = 0.0043, n = 5 adult mice, n = 5 aged mice). E Log2 fold change of the average DCX-positive cells between adult and aged C57BL/6J mice and adult and aged DO mice. F Average DCX-positive cells in the DG of adult C57BL/6J and DO mice (Mann Whitney test, * p = 0.0317, n = 5 adult C57BL/6J mice, n = 5 adult DO mice). G Average DCX-positive cells in the DG of aged C57BL/6J and DO mice (Mann Whitney test, p = 0.1143, n = 4 aged C57BL/6J mice, n = 6 aged DO mice)
    Figure Legend Snippet: Neurogenesis is impaired with age in the Diversity Outbred mouse model and reduced relative to C57BL/6J inbred mice. A Representative confocal microscopy images of the dentate gyrus (DG) of adult (6 month) and aged (18 month) C57BL/6J mice stained for Doublecortin (DCX) (green). B Quantification of the numbers of the average DCX-positive cells in the DG of adult and aged C57BL/6J mice (Mann Whitney U test, * p = 0.0159, n = 5 adult mice, n = 4 aged mice). C Representative confocal microscopy images of the dentate gyrus of adult (6 month) and aged (18 month) Diversity Outbred mice stained for DCX (green). D Quantification of the average DCX-positive cells in the DG of adult and aged Diversity Outbred mice (Mann Whitney test, ** p = 0.0043, n = 5 adult mice, n = 5 aged mice). E Log2 fold change of the average DCX-positive cells between adult and aged C57BL/6J mice and adult and aged DO mice. F Average DCX-positive cells in the DG of adult C57BL/6J and DO mice (Mann Whitney test, * p = 0.0317, n = 5 adult C57BL/6J mice, n = 5 adult DO mice). G Average DCX-positive cells in the DG of aged C57BL/6J and DO mice (Mann Whitney test, p = 0.1143, n = 4 aged C57BL/6J mice, n = 6 aged DO mice)

    Techniques Used: Confocal Microscopy, Staining, MANN-WHITNEY

    Related Articles

    Saline:

    Article Title: Characterization of adult hippocampal neurogenesis in adult and aged genetically diverse mice.
    Article Snippet: .. Sections were blocked in 10% Normal Donkey Serum (Jackson ImmunoResearch) and 1% Triton X-100 in 1X phosphate buffered saline (pH 7.4), then incubated with a rabbit polyclonal anti-Doublecortin primary antibody (1:500; Cell Signaling Technology) in 10% Normal Donkey Serum and 0.1% Triton X-100 overnight. .. Sections were washed in PBS and 0.01% Triton X-100 and incubated with an Alexa Fluor 488 donkey anti-rabbit secondary antibody (1:500; Invitrogen) for two hours.

    Article Title: Characterization of adult hippocampal neurogenesis in adult and aged genetically diverse mice
    Article Snippet: .. Sections were blocked in 10% Normal Donkey Serum (Jackson ImmunoResearch) and 1% Triton X-100 in 1X phosphate buffered saline (pH 7.4), then incubated with a rabbit polyclonal anti-Doublecortin primary antibody (1:500; Cell Signaling Technology) in 10% Normal Donkey Serum and 0.1% Triton X-100 overnight. .. Sections were washed in PBS and 0.01% Triton X-100 and incubated with an Alexa Fluor 488 donkey anti-rabbit secondary antibody (1:500; Invitrogen) for two hours.

    Incubation:

    Article Title: Characterization of adult hippocampal neurogenesis in adult and aged genetically diverse mice.
    Article Snippet: .. Sections were blocked in 10% Normal Donkey Serum (Jackson ImmunoResearch) and 1% Triton X-100 in 1X phosphate buffered saline (pH 7.4), then incubated with a rabbit polyclonal anti-Doublecortin primary antibody (1:500; Cell Signaling Technology) in 10% Normal Donkey Serum and 0.1% Triton X-100 overnight. .. Sections were washed in PBS and 0.01% Triton X-100 and incubated with an Alexa Fluor 488 donkey anti-rabbit secondary antibody (1:500; Invitrogen) for two hours.

    Article Title: Characterization of adult hippocampal neurogenesis in adult and aged genetically diverse mice
    Article Snippet: .. Sections were blocked in 10% Normal Donkey Serum (Jackson ImmunoResearch) and 1% Triton X-100 in 1X phosphate buffered saline (pH 7.4), then incubated with a rabbit polyclonal anti-Doublecortin primary antibody (1:500; Cell Signaling Technology) in 10% Normal Donkey Serum and 0.1% Triton X-100 overnight. .. Sections were washed in PBS and 0.01% Triton X-100 and incubated with an Alexa Fluor 488 donkey anti-rabbit secondary antibody (1:500; Invitrogen) for two hours.



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    Neurogenesis is impaired with age in the Diversity Outbred mouse model and reduced relative to C57BL/6J inbred mice. A Representative confocal microscopy images of the dentate gyrus (DG) of adult (6 month) and aged (18 month) C57BL/6J mice stained for <t>Doublecortin</t> (DCX) (green). B Quantification of the numbers of the average DCX-positive cells in the DG of adult and aged C57BL/6J mice (Mann Whitney U test, * p = 0.0159, n = 5 adult mice, n = 4 aged mice). C Representative confocal microscopy images of the dentate gyrus of adult (6 month) and aged (18 month) Diversity Outbred mice stained for DCX (green). D Quantification of the average DCX-positive cells in the DG of adult and aged Diversity Outbred mice (Mann Whitney test, ** p = 0.0043, n = 5 adult mice, n = 5 aged mice). E Log2 fold change of the average DCX-positive cells between adult and aged C57BL/6J mice and adult and aged DO mice. F Average DCX-positive cells in the DG of adult C57BL/6J and DO mice (Mann Whitney test, * p = 0.0317, n = 5 adult C57BL/6J mice, n = 5 adult DO mice). G Average DCX-positive cells in the DG of aged C57BL/6J and DO mice (Mann Whitney test, p = 0.1143, n = 4 aged C57BL/6J mice, n = 6 aged DO mice)
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    Image Search Results


    Neurogenesis is impaired with age in the Diversity Outbred mouse model and reduced relative to C57BL/6J inbred mice. A Representative confocal microscopy images of the dentate gyrus (DG) of adult (6 month) and aged (18 month) C57BL/6J mice stained for Doublecortin (DCX) (green). B Quantification of the numbers of the average DCX-positive cells in the DG of adult and aged C57BL/6J mice (Mann Whitney U test, * p = 0.0159, n = 5 adult mice, n = 4 aged mice). C Representative confocal microscopy images of the dentate gyrus of adult (6 month) and aged (18 month) Diversity Outbred mice stained for DCX (green). D Quantification of the average DCX-positive cells in the DG of adult and aged Diversity Outbred mice (Mann Whitney test, ** p = 0.0043, n = 5 adult mice, n = 5 aged mice). E Log2 fold change of the average DCX-positive cells between adult and aged C57BL/6J mice and adult and aged DO mice. F Average DCX-positive cells in the DG of adult C57BL/6J and DO mice (Mann Whitney test, * p = 0.0317, n = 5 adult C57BL/6J mice, n = 5 adult DO mice). G Average DCX-positive cells in the DG of aged C57BL/6J and DO mice (Mann Whitney test, p = 0.1143, n = 4 aged C57BL/6J mice, n = 6 aged DO mice)

    Journal: GeroScience

    Article Title: Characterization of adult hippocampal neurogenesis in adult and aged genetically diverse mice

    doi: 10.1007/s11357-025-01749-9

    Figure Lengend Snippet: Neurogenesis is impaired with age in the Diversity Outbred mouse model and reduced relative to C57BL/6J inbred mice. A Representative confocal microscopy images of the dentate gyrus (DG) of adult (6 month) and aged (18 month) C57BL/6J mice stained for Doublecortin (DCX) (green). B Quantification of the numbers of the average DCX-positive cells in the DG of adult and aged C57BL/6J mice (Mann Whitney U test, * p = 0.0159, n = 5 adult mice, n = 4 aged mice). C Representative confocal microscopy images of the dentate gyrus of adult (6 month) and aged (18 month) Diversity Outbred mice stained for DCX (green). D Quantification of the average DCX-positive cells in the DG of adult and aged Diversity Outbred mice (Mann Whitney test, ** p = 0.0043, n = 5 adult mice, n = 5 aged mice). E Log2 fold change of the average DCX-positive cells between adult and aged C57BL/6J mice and adult and aged DO mice. F Average DCX-positive cells in the DG of adult C57BL/6J and DO mice (Mann Whitney test, * p = 0.0317, n = 5 adult C57BL/6J mice, n = 5 adult DO mice). G Average DCX-positive cells in the DG of aged C57BL/6J and DO mice (Mann Whitney test, p = 0.1143, n = 4 aged C57BL/6J mice, n = 6 aged DO mice)

    Article Snippet: Sections were blocked in 10% Normal Donkey Serum (Jackson ImmunoResearch) and 1% Triton X-100 in 1X phosphate buffered saline (pH 7.4), then incubated with a rabbit polyclonal anti-Doublecortin primary antibody (1:500; Cell Signaling Technology) in 10% Normal Donkey Serum and 0.1% Triton X-100 overnight.

    Techniques: Confocal Microscopy, Staining, MANN-WHITNEY